Morning everyone! Hope you are having a nice Friday!
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Personally (taking into account the ones you have):
Kross is great, even if she only has 3 stars.
Once you promote Exusiai, you probably won't need Jessica or May at all, as Kross and Exu can do a lot of the sniper damage needed on a lot of stages
Mountain skill 2 makes him a great solo lane holder (even better when you promote him)
Spot is great too, being able to hold and heal.
Cantabile is good to generate DP + doing some damage early so I guess that's fine, but once you need more (probably once you have more operators or promote those you already have), I would recommend always using either Elysium or Myrtle with her.
For Medics, I guess Lumen and either Silence or Ansel are good enough?
For Arts damage and Aoe damage, yeah, you are... how should I say this...
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Try to use a support unit like Eyjafjalla skill 2 or something.