Ah, 2d is the way. 3d more often than not, feels like a rehash of other assets, personally. One DAZ model is very similar to many others, rare are the times they are distinct for me.
Still, it comes more to me being a sucker for a good and cute artwork
It really depends on the game tbh. I absolutely love 2D and especially pixel art games, but depending on the content and style, 3D can be really good too.