I will play as a fem protag if there is lesbian content and no forced scenes with men. Something about the avatar representing me being even attracted to men makes me feel very uncomfortable even if the same number of dicks are on screen
This is how I feel which is why I don't mind playing female MC games because I don't care to feel immersed. Some good games I've played have female MC's.
I'm open to it in a Kinetic Novel, but in a game with choices playing as a female MC really messes with me. I don't feel like I'm playing "as" them the same way I do a male MC, instead I'm more like a voice on their shoulder. Usually trying to "help them out" and make safe/boring choices.
One exception to this is Good Girl Gone Bad, simply because the writing is good enough to make me want to see very route. I guess that's like removing choices from the game though.