Mostly depends on the game lol, if its a VN a self-insert male MC is more enjoyable while stuff like RPG and unity games i find playing as a female MC more enjoyable
Usually male MC, but I'm willing to play as a female MC if it's either a corruption story with her falling prey to a man or a lesbian femdom story with her domming other women. In other words as long as it includes femsub it's alright in my books!
I prefer male if the game is more focused on the first person perspective so I'll never see the main character, but if I have to constantly see the main character I'd prefer female.
I don't really care... With a male it's fun to check out a bunch of different girls. WIth a girl MC it's nice to see her be a slut. I really don't insert myself into games so it doesn't make be feel a need to play one or the other.
I don't particularly care, and it depends on the context I guess. Male, Female, Futa...
I prefer playing female characters for NTR games though, the perspective is what I prefer with those. I'm not really into playing cucks (or at least it has to share perspective in these games).
I'm really interested in seeing more girls in art I like. For the most part, that means I'll ignore female led games, since it's usually fewer girls and more guys. Exceptions do exist, though... and are highly encouraged