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I use Sandboxie Plus to run any software/games from sources I don't trust isolated from Windows and the Internet (like pirated and free games / apps from unknown developers).
And it's lightweight. It consumes very few resources.

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Description:
Sandboxie is a sandbox-based isolation software for 32-bit and 64-bit Windows NT-based operating systems. It creates a sandbox-like isolated operating environment in which applications can be run or installed without permanently modifying local & mapped drives or the Windows registry. An isolated virtual environment allows controlled testing of untrusted programs and web surfing.
Sandboxie allows you to create virtually unlimited sandboxes and run them alone or simultaneously to isolate programs from the host and each other, while also allowing you to run as many programs simultaneously in a single box as you wish.
Features
Sandboxie is available in two editions, Plus and Classic. They both share the same core components, this means they have the same level of security and compatibility. What's different is the availability of features in the user interface.Sandboxie Plus has a modern Qt-based UI, which supports all new features that have been added since the project went open source:
- Snapshot Manager - takes a copy of any box in order to be restored when needed
- Maintenance mode - allows to uninstall/install/start/stop Sandboxie driver and service when needed
- Portable mode - you can run the installer and choose to extract all files to a directory
- Additional UI options to block access to Windows components like printer spooler and clipboard
- More customization options for Start/Run and Internet access restrictions
- Privacy mode sandboxes that protect user data from illegitimate access
- Security enhanced sandboxes that restrict the availability of syscalls and endpoints
- Global hotkeys to suspend or terminate all boxed processes
- A network firewall per sandbox which supports Windows Filtering Platform (WFP)
- The list of sandboxes can be searched with the shortcut key Ctrl+F
- A search function for Global Settings and Sandbox Options
- Ability to import/export sandboxes to and from 7z files
- Integration of sandboxes into the Windows Start menu
- A browser compatibility wizard to create templates for unsupported browsers
- Vintage View mode to reproduce the graphical appearance of Sandboxie Control
- A troubleshooting wizard to assist users with their problems
- An Add-on manager to extend or add functionality via additional components
- Protections of sandboxes against the host, including the prevention of taking screenshots
- A trigger system to perform actions, when a sandbox goes through different stages, like initialization, box start, termination or file recovery
- Make a process not sandboxed, but its child processes sandboxed
What you can do:
- You can install and run any game or software inside a Sandboxie sandbox using right click / run isolated on a Sandbox. (e.g: Any pirated 3D AAA games and cracked sofware, or lewd games)
- I have Sandboxie controlled Box and folders where I unzip/install any software or game. Then I double click/execute the game inside that windows folder and it automatically opens inside a sandbox, completely isolated from the SO and Internet (if you choose to do so. It can access to internet adding it to a whitelist or using a global setting for that sandbox folder).
- Run multiple instances of the same software with multiple accounts (like multiple Steam accounts, as in the screenshot.)
- Browse the web. I run a chromium browser (with sandbox) inside a Sandboxie sandbox. So if there is a virus using a zero-day bug on a web site that escalates privileges and bypasses the chromium sandbox, it would also have to bypass the sandboxie sandbox. Difficult, but not impossible.
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(official site)
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It scans for virus using 74+ antivirus and 6 automated sandboxes to analyse software behaviour.
Inspired by these two threads:
Virus Warning
VM for running adult games
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